Study of the NATURal History, Epidemiological, Clinical, Diagnostic and Therapeutic Aspects of CELiac Disease and Non-celiac Enteropathies
Recruiting now
Conditions studied: Celiac Disease
In brief
Celiac disease is a chronic immune-mediated enteropathy triggered by gluten intake, which affects the small intestine in genetically susceptible subjects (HLA-DQ2 and/or HLA-DQ8). Affecting both children and adults, it is among the most common genetically determined disorders in Western countries. The disease is characterized by clinical manifestations (mainly digestive symptoms and signs of intestinal malabsorption), the presence of specific antibodies (tissue transglutaminase and endomysium) and enteropathy. Currently, the only treatment for celiac disease is a strict gluten-free diet for life. The main objective of the NATURCEL registry (Study of the NATURal history, epidemiological, clinical, diagnostic and therapeutic aspects of celiac disease and non-celiac enteropathies) is to collect a wide range of data (epidemiological, clinical, genetic, immunological, etc.) for scientific and translational purposes. The registry will include individuals diagnosed with celiac disease or other gluten-related disorders, as well as patients with non-celiac enteropathies evaluated for suspected celiac disease. In the future, the project also aims to establish a biobank-an organized repository of biological samples-to further support scientific and medical research in this field.
Key facts
- Study ID
- NCT07070596
- Run by
- Hospital Mutua de Terrassa
- People needed
- 1000
- Starts
- 2025-06-01
- Expected to finish
- 2030-01-01
- Last updated by the study team
- 2025-07-17
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Individuals under diagnostic evaluation for celiac disease
You may not qualify if…
- Failure to sign informed consent
Where it is running
- Hospital Universitari MútuaTerrassa — Terrassa, Barcelona, Spain (enrolling)
Full record on ClinicalTrials.gov
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