The Effect of Dexmedetomidine on Agitation During Weaning From Mechanical Ventilation

Recruiting now · Not applicable

Conditions studied: Dexmedetomidine

In brief

This study aims to evaluate the effect of dexmedetomidine on the level of agitation during the weaning process from mechanical ventilation in critically ill patients.

Key facts

Study ID

NCT07066605

Run by

Sohag University

People needed

62

Starts

2025-06-13

Expected to finish

2025-12-30

Last updated by the study team

2025-07-15

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult ICU patients (≥18 years).
• On mechanical ventilation ≥24 hours.
• Clinically ready for weaning.
• Agitation score RASS ≥ +1 during spontaneous breathing trial.
• Intubation for at least 4 days: 2 weeks.

You may not qualify if…

• Known hypersensitivity to dexmedetomidine.
• Hemodynamic instability (HR < 50 bpm or MAP < 60 mmHg).
• Neurological impairment affecting level of consciousness.
• Pregnancy or lactation.

Where it is running

• Sohag University Hospital — Sohag, Egypt (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.