Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
Recruiting now
Conditions studied: Anterior Uveitis (AU), Birdshot Chorioretinitis, Behcet Disease, Herpes Simplex Virus, Juvenile Idiopathic Arthritis (JIA), Spondyloarthritis (SA), Sarcoidosis, Posterior Vitreous Detachment
In brief
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.
Key facts
- Study ID
- NCT07065747
- Run by
- Oregon Health and Science University
- People needed
- 125
- Starts
- 2024-09-01
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2025-07-17
Who can join
Age: 5 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Uveitis Group: Eyes with active intraocular inflammation and a clinical diagnose of spondyloarthritis/HLA-B27 associated anterior uveitis, Juvenile Idiopathic Arthritis (JIA) associated chronic anterior uveitis, Herpes Simplex Virus (HSV) anterior uveitis, Birdshot chorioretinitis, Behcet disease uveitis, sarcoidosis associated uveitis, uveitis of any additional type, or uveitis masquerade.
- Posterior Vitreous Detachment Group: Eyes with vitreous floaters and posterior vitreous detachment (PVD).
- Healthy/Control Group: Healthy eyes with no history of uveitis, PVD, or previous eye surgery.
You may not qualify if…
- Inability to give informed consent.
- Inability to maintain stable fixation for OCT imaging.
- Inability to commit to required visits to complete the study.
- Pregnancy and breastfeeding.
Where it is running
- Casey Eye Institute - Oregon Health & Science University — Portland, Oregon, United States (enrolling)
Full record on ClinicalTrials.gov
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