Effetivity of Dutasteride and Aloe Vera Extract Combination on Angiogenesis and Obstruction on Benign Prostatic Hyperplasia

Recruiting now · Phase 1

Conditions studied: BPH (Benign Prostatic Hyperplasia)

In brief

This study is a double blinded RCT with pre-post test design on the effect of combination of dutasteride and aloe vera, compared to dutasteride only, on uroflowmetry results, prostate volume, and VEGF serum level among patients with benign prostate hyperplasia. The treatment was given for 12 weeks

Key facts

Study ID

NCT07065682

Run by

Universitas Diponegoro

People needed

84

Starts

2023-07-01

Expected to finish

2027-12-01

Last updated by the study team

2025-07-15

Who can join

Age: 50 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed with BPH clinically or radiologically (prostate volume > 30 gram, Qmax <15 mL/s)
• Willing to participate to the study

You may not qualify if…

• Clinically or radiologically suspected of having prostatic cancer
• Previous prostatic surgery
• Patients with urinary retention
• Patients with BPH complications: urinary tract infections, urolithiasis, or hydroneprhosis
• Previously consumed alpha blocker or 5ARI in the last 6 months
• Have consumed aloe vera extract routinely

Where it is running

• RSUD Karawang — Karawang, West Java, Indonesia (enrolling)

Full record on ClinicalTrials.gov

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