Effect of Rehabilitation at Moderate Altitude on Airway Resistance Measured With Forced Oscillation Technique in COPD-patients

Recruiting now · Not applicable · Has a placebo group

Conditions studied: COPD

In brief

Airway resistance will be measured using the forced oscillation technique (FOT). The parameters Rrs, Xrs, and ∆Xrs will be compared before and after a pulmonary rehabilitation cycle at moderate altitude. Additionally, the differences between low and moderate altitude will also be examined.

Key facts

Study ID: NCT07063563
Run by: Eastern Switzerland University of Applied Sciences
People needed: 52
Starts: 2025-07-23
Expected to finish: 2025-12-31
Last updated by the study team: 2025-07-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Aged ≥18 years
Stable clinical condition for >3 weeks (e.g., no exacerbations)
Resting SpO₂ ≥88% and exercise-induced hypoxemia defined as a drop in SpO₂ of ≥4% and/or a level below 90% during the 6MWT
Informed consent documented by signature

You may not qualify if…

Severe daytime resting hypoxemia (SpO₂ <88%)
Long-term oxygen therapy
Unstable clinical condition requiring adjustment of pharmacological or other treatment modalities, need for intensive care, or presence of relevant severe comorbidities
Inability to comply with study procedures (e.g., due to language barriers, psychological disorders, neurological or orthopedic impairments, walking disability, or inability to ride a bicycle)
Women who are pregnant or breastfeeding
Enrolment in another clinical trial involving active treatment

Where it is running

National center for cardiology and internal medicine — Bishkek, Kyrgyzstan, Kyrgyzstan (enrolling)
Eastern Switzerland University of Applied Sciences — Sankt Gallen, Canton of St. Gallen, Switzerland

Full record on ClinicalTrials.gov

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