Effect of Vitamin D Deficiency on the Frequency and Severity of Spinal Anesthesia-Induced Hypotension in Pregnant Women Undergoing Cesarean Section

Recruiting now

Conditions studied: Spinal Anesthesia-induced Hypotension, Vitamin D Deficiency, Cesarean Section

In brief

Spinal anesthesia-induced hypotension remains a common and significant complication during cesarean sections, posing risks for both mother and fetus. Vitamin D deficiency, frequently observed in pregnant women, is associated with altered vascular function and potential hemodynamic instability. This prospective observational study aims to investigate whether vitamin D deficiency is associated with an increased incidence and severity of spinal anesthesia-induced hypotension in pregnant women undergoing elective cesarean delivery. Vitamin D levels will be measured preoperatively, and intraoperative hemodynamic parameters will be closely monitored. The findings could contribute to improved management strategies for pregnant patients at risk of severe hypotension.

Key facts

Study ID

NCT07057362

Run by

Duzce University

People needed

140

Starts

2025-03-01

Expected to finish

2025-12-30

Last updated by the study team

2026-01-06

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Pregnant women aged 18 years or older
• Scheduled for elective cesarean delivery under spinal anesthesia
• Able and willing to provide written informed consent

You may not qualify if…

• Emergency cesarean sections
• History of significant cardiovascular disease (e.g., arrhythmia, heart failure)
• Known neurological disorders affecting autonomic function
• Current vitamin D supplementation within the past 30 days
• Inability to undergo blood sampling or provide valid hemodynamic data
• Contraindication to spinal anesthesia

Where it is running

• Duzce University Faculty of Medicine, Department of Anesthesiology and Reanimation — Düzce, Merkez, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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