Technologies and Systems for Assessing Human Energy Metabolism and Nutritional Rehabilitation
Recruiting now
Conditions studied: Energy Metabolism, Nutrition, Healthy
In brief
The objective of this observational study is to integrate the doubly labeled water (DLW) database from healthy individuals with multimodal data-including, but not limited to, weight, height, age, sex, race, elevation-from cohorts undergoing rehabilitation following movement impairments or neurological injuries. Machine learning algorithms will be used to develop injury-specific predictive models of energy requirements. The primary research question is: How does energy metabolism change during the rehabilitation process in individuals recovering from traumatic brain injury, stroke, or major surgical procedures? To answer this, participants will undergo a comprehensive set of assessments, including measurements of height and weight, body composition, resting metabolic rate, physical activity levels, total energy expenditure, psychological health, food intake and hunger ratings, sleep quality, cognitive performance, non-invasive brain function monitoring, and gait analysis. Fecal and blood samples will also be collected for untargeted metabolomics analysis.
Key facts
- Study ID
- NCT07056504
- Run by
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
- People needed
- 80
- Starts
- 2025-07-09
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2025-09-02
Who can join
Age: 20 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male and female participants aged 20 to 70 years old;
- Rehabilitation patients with stroke or motor injuries;
You may not qualify if…
- Loss of autonomous mobility;
- Loss of consciousness;
- Individuals with metallic implants (e.g., pacemakers);
- Severe metabolic diseases (e.g., diabetes, other hereditary metabolic disorders);
- Patients with claustrophobia;
- Individuals with anorexia nervosa;
- Women in the preconception period, pregnancy, or lactation;
- Uremic patients;
- Inability to lie flat for one hour.
Where it is running
- Guangdong Jianxiang Hospital Group — Foshan, Guangdong, China (enrolling)
Full record on ClinicalTrials.gov
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