Oral Calcium Supplementation in Labor
Completed · Phase 2/Phase 3
Conditions studied: Uterine Contraction, Labor Complication, Labor Active Dilated Cm, Labor Dystocia, Labor Duration, Labor, Labor Delivery
In brief
The goal of this clinical trial is to learn if oral calcium carbonate can improve uterine contractions and labor outcomes in term pregnancies. It will also evaluate the safety of calcium carbonate when used during labor. The main questions it aims to answer are: Does oral calcium carbonate increase uterine contraction strength? Does it lead to shorter labor duration or higher vaginal delivery rates? What side effects or complications, if any, occur with calcium carbonate use during labor? Researchers will compare oral calcium carbonate to no treatment to see if it helps improve labor efficiency and reduce cesarean delivery rates. Participants will: Be randomly assigned to receive either 2,000 mg of oral calcium carbonate or no intervention Undergo monitoring with an intrauterine pressure catheter to measure contraction strength Be observed for two hours without oxytocin to assess calcium's direct effect on contractions Have data collected on labor progression, delivery outcomes, and neonatal health
Key facts
- Study ID
- NCT07056062
- Run by
- Arrowhead Regional Medical Center
- People needed
- 89
- Starts
- 2024-04-30
- Expected to finish
- 2025-05-30
- Last updated by the study team
- 2025-07-09
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Had an intrauterine pressure catheter in place
- Term gestation, greater than or equal to 37 weeks of gestation
- Singleton pregnancy
- Cephalic presentation
- > 18 years of age
You may not qualify if…
- incarceration
- multiple gestation
- active illicit drug use
- abnormal clinical pelvimetry
- Suspected fetal macrosomia defined as estimated fetal weight ≥4250 grams
- intrauterine growth restriction
- abnormal placentation
- prior cesarean delivery
- maternal history of arrhythmia
- hyperparathyroidism
- heart failure
- renal or hepatic failure
- nephrolithiasis
- receipt of medications known to affect uterine contractility-such as magnesium sulfate, terbutaline, or recent misoprostol in the last four hours
Where it is running
- Arrowhead Regional Medical Center — Colton, California, United States
Full record on ClinicalTrials.gov
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