The Efficacy of Additional Motor Training Dosage During the Early Stages Post Stroke on the Upper Extremity Recovery
Recruiting now · Not applicable
Conditions studied: Stroke, Hemiplegia and Hemiparesis
In brief
Intervention abstract Background: Stroke is the leading cause of long-term disability, and the second leading cause of death in the western world. Most stroke survivors will suffer from motor and cognitive disturbances for the rest of their life, which negatively affects their normal daily life. Despite the decline in stroke-related mortality over the past decades, the outcome of rehabilitation programs does not improve, and is predictable regardless of the program used. Still, several human and animal studies show that high capacity of training in the early stages post stroke improve motor recovery. This notion is far from being well established. Aim: Studying the effect of high-dosage, high-intensity training program in the subacute period on upper extremity motor recovery. Population: Stroke survivors. Study duration: 6 months. Study protocol: Participants will receive additional technology-based upper extremity training for 120 min/day, 5d/w, 4 weeks. They will be monitored pre and post training, and 6 months post-stroke. Outcome measures will include clinical, kinematic and adherence measures (see complete list in the protocol).
Key facts
- Study ID
- NCT07056049
- Run by
- Adi Negev-Nahalat Eran
- People needed
- 50
- Starts
- 2025-07-13
- Expected to finish
- 2027-07-15
- Last updated by the study team
- 2025-07-17
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18 years
- Ischemic or hemorrhagic stroke (hemispheric or brainstem) confirmed by CT or MRI
- First-ever stroke or previous stroke with no upper extremity weakness
- 1 week ≤ Time after stroke onset ≤ 6 weeks
- Active shoulder flexion of at least 20◦ and partial wrist and/or finger active movement
- Ability to provide inform consent
You may not qualify if…
- A painful shoulder limiting an active forward reach
- Severe spasticity or non-neural loss of range of motion
- Cognitive or communication impairments as determined by the clinical team Unstable medical conditions
Where it is running
- Adi Negev-Nahalat Eran — Ofakim, Israel (enrolling)
- Adi Negev-Nahalat Eran — Ofakim, Israel
Full record on ClinicalTrials.gov
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