Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section

Recruiting now · Phase 4

Conditions studied: Pruritus Caused by Drug

In brief

This study compares the incidence of pruritus (itching) requiring treatment between two doses of intrathecal morphine (0.1 mg vs 0.2 mg) when used for spinal anesthesia during cesarean section. The study aims to determine if the lower dose (0.1 mg) can reduce pruritus incidence while maintaining adequate pain relief.

Key facts

Study ID

NCT07054775

Run by

Khon Kaen University

People needed

69

Starts

2025-06-01

Expected to finish

2025-11-30

Last updated by the study team

2025-07-08

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may not qualify if…

• Contraindication to spinal anesthesia or study drugs
• Refusal to participate in the study
• BMI ≥ 40 kg/m²
• History of systemic skin disease or current itchy skin condition
• Use of antihistamines or anti-pruritic medications within 3 days prior to surgery

Where it is running

• Faculty of Medicine, Khon Kaen University — Khon Kaen, Thailand (enrolling)
• Thepakorn Sathitkarnmanee — Khon Kaen, Thailand (enrolling)

Full record on ClinicalTrials.gov

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