Use of a New Diagnostic Tool in the Detection and Characterization of Endometriosis Lesions

Recruiting now · Not applicable

Conditions studied: Endometriosis

In brief

Diagnostic wandering is one of the characteristics of endometriosis due to great anatomical and clinical variability but also due to poorly relevant diagnostic examinations. \[18F\]-FES PET/CT could on the one hand improve diagnosis by showing greater sensitivity than MRI and on the other hand make it possible to quantify and characterize the expression of ER from diagnosis and thus helping to guide therapeutic care. We will thus attempt to correlate the intensity of \[18F\]-FES PET/CT with the expression of estrogen receptors and the intensity of pain.

Key facts

Study ID: NCT07053982
Run by: University Hospital, Toulouse
People needed: 20
Starts: 2026-03-23
Expected to finish: 2028-03-01
Last updated by the study team: 2026-03-25

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

Cases:
Painful patients with a VAS ≥ 4 treated surgically for painful symptoms related to endometriosis;
Controls:
Patient with a VAS < 4 treated surgically for endometriosis in the context of infertility;
Age > 18 years;
Patient who provided informed consent;
Patients who underwent a preoperative MRI and were not contraindicated for [18F]-FES PET/CT;
Patient who underwent surgery mid-cycle;
Affiliation to a social security scheme

You may not qualify if…

Patient treated for endometriosis without surgery;
Pregnant patient
Patient taking hormone therapy
Menopausal patient
Hypersensitivity to the active substance (Fluoroestradiol (18F)) or to any of the excipients
Patient under legal protection
Claustrophobic patient

Where it is running

Toulouse, Rangueil Hospital — Toulouse, France (enrolling)

Full record on ClinicalTrials.gov

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