Patient Navigation and the Planning Advance Care Together Website to Improve Goals of Care Conversations in Hematopoietic Cell Transplant Survivors, IMPACT-HCT Trial

Recruiting now · Not applicable

Conditions studied: Hematopoietic and Lymphatic System Neoplasm

In brief

This clinical trial evaluates the impact of patient navigation and the Planning Advance Care Together (PACT) website, either alone or in combination with one another, on advanced care planning (ACP) in patients with blood cancers who received a hematopoietic cell transplant (HCT). Engagement in ACP, including having goals of care conversations, improves quality of care at the end of life and supporting this should be included in all cancer survivorship care. Patient navigation is a healthcare service that is designed to guide a patient through the healthcare system and reduce barriers to timely screening follow-up, diagnosis, treatment, and supportive care. PACT is a web-based tool that provides information about ACP, assistance with documents for advanced directives, a supportive network and a forum for discussions about ACP. Patients who engage in ACP are more likely to have higher quality of life at the end of life, receive the care they want, die where they prefer, utilize hospice effectively, and are less likely to receive futile, aggressive care at the end of life. For HCT survivors at ongoing risk of death and other disease-related complications, having a plan in place for care they want is critical. Patient navigation and/or the PACT website may improve ACP, including completion of advance care directives and goals of care conversations, in patients with blood cancers who received an HCT.

Key facts

Study ID

NCT07052630

Run by

Fred Hutchinson Cancer Center

People needed

40

Starts

2025-10-21

Expected to finish

2026-10-31

Last updated by the study team

2026-06-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Received a transplant for a hematologic malignancy
• Current age 18 years of age or older
• Currently 1 to 5 years after HCT
• Ability to speak and read English
• Has not completed all advance directives and/or had a goals of care (GOC) conversation with their physician
• Access to the internet (via computer, tablet, or mobile device)

You may not qualify if…

• Unable to provide informed consent
• Uncontrolled psychiatric conditions (confirmed through electronic health record [EHR] by study staff)

Where it is running

• Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington, United States (enrolling)

Full record on ClinicalTrials.gov

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