Antibiotic Treatment for Pneumonia Caused by Stenotrophomonas Maltophilia in ICU Patients

Recruiting now

Conditions studied: Pneumonia, Ventilator-Associated, Stenotrophomonas Maltophilia, Intensive Care Units, Anti-Bacterial Agents, Drug Resistance, Bacterial

In brief

This study looks at how different antibiotic treatments affect patients in intensive care who have pneumonia caused by the bacteria Stenotrophomonas maltophilia. It compares using one antibiotic versus two antibiotics, and treatment lengths of 7 days versus 14 days, to see which approach helps patients survive better. The study also examines how resistant the bacteria are to antibiotics and how often the pneumonia comes back.

Key facts

Study ID

NCT07052604

Run by

Centre Hospitalier de Saint-Denis

People needed

300

Starts

2023-12-15

Expected to finish

2025-09-15

Last updated by the study team

2025-07-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (age ≥ 18 years)
• Hospitalized in Medical Intensive Care Unit between January 1, 2018, and December 31, 2023
• Intubated and mechanically ventilated
• Diagnosed with ventilator-associated pneumonia caused by Stenotrophomonas maltophilia

You may not qualify if…

• Patients under 18 years old
• Patients who refuse the use of their data for research purposes

Where it is running

• Centre Hospitalier de Saint-Denis — Saint-Denis, France, France (enrolling)

Full record on ClinicalTrials.gov

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