Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome
Recruiting now · Not applicable
Conditions studied: Post COVID-19 Syndrome, Functional Inspiratory Muscle Training, Core Stabilization
In brief
This study aims to investigate the effects of core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome. Participants diagnosed with post-COVID-19 syndrome will be randomly assigned to two groups using stratified computer-assisted randomization. One group will undergo an 8-week core stabilization training, while the other will receive combined core stabilization and IMT training. Exercise training will be conducted three times a week, with each session lasting 50 minutes. Comprehensive pre- and post-intervention assessments will be conducted, including exercise capacity, respiratory and peripheral muscle strength, trunk endurance, balance, anxiety, depression, and fatigue levels. The primary outcome measures are respiratory muscle strength and trunk endurance. Participants must be aged 18-65 years, have at least a primary education level, speak Turkish, and be classified as level 2-3 on the Post-COVID-19 Functional Status Scale (PCFS). Eligible participants will be referred by the Internal Medicine Department at Hacettepe University. The study will utilize various assessment tools, including maximal inspiratory/expiratory pressure (MIP/MEP) tests, Functional Movement Screen (FMS), plank and Sorenson endurance tests, the Timed Up and Go Test for balance, handgrip and knee extension strength tests, body composition analysis, and the SF-36 quality of life questionnaire.
Key facts
- Study ID
- NCT07051954
- Run by
- Hacettepe University
- People needed
- 40
- Starts
- 2025-09-15
- Expected to finish
- 2026-12-30
- Last updated by the study team
- 2026-01-14
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosed with Post-COVID-19 Syndrome.
- Literate and able to understand study procedures.
- Aged between 18 and 65 years.
- Willing to voluntarily participate in the study.
- Classified as functional class 2-3 according to the Post-COVID-19 Functional Status Scale (PCFS).
- Clinically stable; comorbid conditions such as hypertension or diabetes must be controlled.
- No orthopedic or neurological conditions that would prevent assessment of peripheral muscle strength, balance, or exercise capacity.
You may not qualify if…
- History of recent myocardial infarction or pulmonary embolism.
- Presence of uncontrolled chronic diseases.
- Any orthopedic or neurological disorders that limit mobility.
- Neurological impairments (e.g., cerebrovascular disease) or psychiatric disorders that impair cooperation or compliance with exercise testing.
Where it is running
- Hacettepe University — Ankara, Çankaya, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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