Efficacy of a Personalized, Response-based Transdiagnostic Intervention for Emotional Disorders Delivered Via the Internet: A Protocol for an Adaptive Randomized Controlled Trial
Starting soon · Not applicable
Conditions studied: Emotional Disorders, Anxiety, Depression, Unipolar
In brief
This adaptive randomized controlled trial evaluates the efficacy of a transdiagnostic, internet-delivered psychological intervention for emotional disorders, tailored to patient´s early clinical response. 366 adults with clinically significant symptoms of depression and/or anxiety will begin a 12 module self-applied program. Based on sympton reduction after the first three modules, participants will be classified as early or late responders and randomized into different experimental arms. The main hypothesis is that a hybrid format (self-applied modules plus synchronous sessions with a therapist) will yield better outcomes for late responders. Outcomes include symptom reduction, emotional regulation and internet based therapheutic alliance.
Key facts
- Study ID
- NCT07051148
- Run by
- Universitat Jaume I
- People needed
- 366
- Starts
- 2027-05-01
- Expected to finish
- 2030-07-01
- Last updated by the study team
- 2026-05-27
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Spanish speakers
- OASIS score +/= 8
- ODSIS score +/= 7
- Access to Internet
You may not qualify if…
- Severe mental disorder: schizophrenia/bipolar disorder
- Active substance abuse
- High suicide risk
- Ongoing psychological/pharmacological treatment
- Interfering physical illness
Full record on ClinicalTrials.gov
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