Dual-chamber Patient-controlled Analgesia for Postoperative Recovery

Recruiting now · Not applicable

Conditions studied: Morbid Obesity, PCA, Analgesia, PONV

In brief

Postoperative nausea and vomiting (PONV) are the most common complications that can occur after general anesthesia. Postoperative use of opioids and morbid obesity have been reported as risk factors of PONV. In this study, the investigators aimed to compare the degree of postoperative side effects and pain control when an intravenous patient-controlled analgesia combining fentanyl and ketorolac via a dual-chamber device was provided to participants undergoing laparoscopic sleeve gastrectomy.

Key facts

Study ID

NCT07051109

Run by

Seoul National University Bundang Hospital

People needed

92

Starts

2022-10-11

Expected to finish

2026-03-11

Last updated by the study team

2025-07-03

Who can join

Age: 19 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Adult females aged 19 to 65 years
• American Society of Anesthesiologists physical status (ASA class) 1 to 3
• Patients scheduled for laparoscopic sleeve gastrectomy under general anesthesia
• Patients requesting the use of IV-PCA after surgery

You may not qualify if…

• Patients with hypersensitivity to the drugs used in this study (Ketorolac, Fentanyl)
• Patients with alcohol or drug dependence, long-term use of opioids or analgesics
• Patients with liver disease or renal failure
• Patients with peptic ulcer, patients with gastrointestinal bleeding predisposition
• Patients with suspected cerebrovascular hemorrhage, organic disorders of the head related to increased intracranial pressure
• Patients with bronchial asthma or bronchospasm symptoms
• Patients with severe respiratory depression
• Nasal polyps, angioedema
• Patients with or history of convulsive disease
• Patients for whom the use of neuromuscular blocking agents is contraindicated

Where it is running

• Seoul National University Bundang Hospital — Seongnam-si, Gyunggi-do, South Korea (enrolling)

Full record on ClinicalTrials.gov

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