Application of Remimazolam, Dexmedetomidine, and Esketamine in Pediatric Preoperative Sedation

Recruiting now · Not applicable

Conditions studied: Remimazolam, Dexmedetomidine, Esketamine

In brief

By comparing the application effects of three drugs in pediatric preoperative sedation, this study explores the optimal medication regimen, aiming to provide safer, more effective, and more personalized medication options for pediatric preoperative sedation. Additionally, this research will also focus on the impact of these three drugs on postoperative agitation in children, offering valuable references for the overall management of pediatric surgical anesthesia.

Key facts

Study ID

NCT07050212

Run by

Maternal and Child Health Hospital of Hubei Province

People needed

150

Starts

2025-04-01

Expected to finish

2026-03-01

Last updated by the study team

2025-07-10

Who can join

Age: 2 and older, up to 5. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Children aged 2 to 5 years old
• the American Society of Anesthesiologists (ASA) physical status of Class I
• scheduled for adenotonsillectomy under general anesthesia, will be included.

You may not qualify if…

• Abnormal lung function and respiratory system function
• airway obstruction or deformity, history of mental illness
• electrocardiogram indicating bradycardia
• history of cardiac disease

Where it is running

• Maternal and Child Health Hospital of Hubei Province — Wuhan, Hubei, China (enrolling)

Full record on ClinicalTrials.gov

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