Remimazolam and Emergence Delirium in Pediatrics

Recruiting now · Phase 4

Conditions studied: Pediatric, Neurosurgery, Sevoflurane Anesthesia, Remimazolam, Emergence Delirium

In brief

Emergence delirium is a common complication in pediatrics undergoing neurosurgery. Previous study showed that a single bolus of remimazolam was associated with lower incidence of postoperative agitation. Present study was designed to investigate if remimazolam supplemented to sevoflurane anesthesia could decrease the risk of emergence delirium in pediatrics undergoing neurosurgery.

Key facts

Study ID

NCT07046364

Run by

Peking University First Hospital

People needed

248

Starts

2025-01-01

Expected to finish

2027-01-01

Last updated by the study team

2025-07-01

Who can join

Age: 1 and older, up to 6. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 1 to 6 years old
• Planned to receive elective neurosurgery under general anesthesia
• Expected duration of surgery > 1 hour

You may not qualify if…

• Allergy to benzodiazepine
• Use of other sedatives within 12 hours before surgery such as benzodiazepines, propofol, chloral hydrate, etc.,
• ASA classification IV or above
• Unable to complete emergence delirium assessment, such as language, hearing or vision impairment.

Where it is running

• Peking University First Hospital — Beijing, Beijing Municipality, China (enrolling)
• Peking University First Hospital — Beijing, Beijing Municipality, China

Full record on ClinicalTrials.gov

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