PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture

Recruiting now · Not applicable

Conditions studied: Hip Fracture, Analgesia Post Fracture

In brief

Pericapsular Nerve Group Block (PENG) is an effective regional anaesthesia modality in providing analgesia following neck of femur fracture. Continuous PENG techniques, using indwelling catheters and infusions of local anaesthetic, facilitate the continuation of analgesia for a number of days following hip fracture surgery. It is unclear from the published literature whether an optimal strategy of local anaesthetic delivery has been characterized. Similar doses of local anaesthetic agents can be administered by either continuous infusion or timed intermittent bolus. It is unclear whether one dosing strategy is superior to the other in the context of hip fracture analgesia. The study aims to evaluate the clinical efficacy of both dosing strategies in patients undergoing hip fracture surgery.

Key facts

Study ID

NCT07046052

Run by

University College Cork

People needed

150

Starts

2024-03-28

Expected to finish

2026-01-07

Last updated by the study team

2025-07-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English-speaking
• over the age of 18 years
• hemiarthroplasty for fractured neck of femur
• able to provide written consent.

You may not qualify if…

• under 50kg body weight.
• unable to provide consent due to incapacity
• pregnant women
• vulnerable adults under state guardianship
• Patients with pre-existing chronic pain disorders or with a history of long-term opioid use
• those with contraindications to a peripheral nerve block such as local site infection, allergy to local anaesthetic or those who are coagulopathic

Where it is running

• Cork University Hospital — Cork, Cork, Ireland (enrolling)

Full record on ClinicalTrials.gov

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