Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD

Recruiting now · Not applicable

Conditions studied: COPD

In brief

This study aims to evaluate how airway inflammation, lung function, and symptoms change over time in people with chronic obstructive pulmonary disease (COPD). Airway inflammation will be assessed using a simple breath test (FeNO) and a small blood sample to measure eosinophils, a type of white blood cell. Participants will be followed for one year, with three study visits (at the start, 6 months, and 12 months). The goal is to understand how these markers evolve and whether they differ between people who experience a worsening of symptoms (called exacerbations) and those who remain stable. All tests except for a small extra blood draw are part of routine COPD care. Participation does not affect standard treatment.

Key facts

Study ID

NCT07045948

Run by

Universitair Ziekenhuis Brussel

People needed

100

Starts

2025-07-14

Expected to finish

2028-06-01

Last updated by the study team

2025-09-11

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged ≥ 40 years
• Diagnosed with COPD according to GOLD criteria
• Attending routine follow-up visits every 6 months
• Ability to provide informed consent

You may not qualify if…

• Recent respiratory tract infection or exacerbation (either moderate or se-vere) (<4 weeks before inclusion)
• Dominant asthmatic phenotype (ACO with asthma predominance)
• Severe comorbidities interfering with participation or follow-up

Where it is running

• Universitair Ziekenhuis Brussel — Jette, Belgium (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.