Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness

Recruiting now · Not applicable

Conditions studied: Alzheimer Disease, Aging, Lifestyle Factors, Cognitive Impairment, Yoga, Time Restricted Eating, Diet Modification

In brief

The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau protein), physical fitness, and metabolism in older adults at increased risk of developing Alzheimer's disease.

Key facts

Study ID

NCT07042087

Run by

St. Anne's University Hospital Brno, Czech Republic

People needed

48

Starts

2024-11-01

Expected to finish

2026-12-01

Last updated by the study team

2025-06-27

Who can join

Age: 60 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 60-80 years
• Diagnosis of Subjective Cognitive Impairment (SCI) or Mild Cognitive Impairment (MCI)
• mini-mental-scale (MMSE) score between 24-30
• Positive plasma pTau217 biomarker
• Stable dose of iAChE therapy (if applicable)
• Ability to participate in a 9-month intervention

You may not qualify if…

• Stroke or myocardial infarction within the past year
• Decompensated internal conditions (e.g., severe heart failure, kidney failure, unstable diabetes, GLP1 agonist therapy)
• Long-term psychiatric treatment (except well-managed depression)
• Neurological conditions affecting mobility or cognition (e.g., Parkinson's disease, severe tremor, epilepsy)
• Severe sensory or motor impairment preventing protocol participation
• Active cancer treated within the past 5 years
• Poor anticipated compliance (e.g., transport issues, time constraints, non-cooperation)
• Concurrent participation in another clinical study
• Unstable iAChE medication regimen
• Substance or alcohol dependence

Where it is running

• Fnusa/ Icrc — Brno, Czechia (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.