Evaluating Postoperative Pain and Antibacterial Effect of Ultrasonic and 980 nm Diode Laser Combination

Recruiting now · Not applicable

Conditions studied: Post Operative Pain

In brief

This study is a parallel randomized controlled clinical trial that was designed and interpreted according to Preferred Reporting Items for Randomized Trial in Endodontics (PRIRATE) 2020 guidelines. Patients of age range between 20 and 35 years old from the outpatient clinic of Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University will participate in this study. These patients have single rooted teeth with necrotic pulp and periapical radiolucency. Patients will be informed about all the study's procedures. They will be included in the study after fulfilling the inclusion criteria and sign an informed consent.Inclusion Criteria: * Patients have mature teeth with closed apex. * Single rooted teeth with root canal form type I. * Asymptomatic. * Have Periapical radiolucency with diameter up to 5 mm. * Restorable teeth. Exclusion Criteria: * Patients with symptomatic apical periodontitis. * Systemic disease. * Physical or mental disability. * Root fracture and tooth mobility.

Key facts

Study ID

NCT07041736

Run by

Al-Azhar University

People needed

120

Starts

2025-08-03

Expected to finish

2026-05-01

Last updated by the study team

2026-03-17

Who can join

Age: 20 and older, up to 35. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients have mature teeth with closed apex.
• Single-rooted teeth with root canal form type I.
• Asymptomatic.
• Have periapical radiolucency with a diameter of up to 5 mm.
• Restorable teeth.

You may not qualify if…

• Patients with symptomatic apical periodontitis.
• Systemic disease.
• Physical or mental disability.
• Root fracture and tooth mobility.

Where it is running

• from the outpatient clinic of Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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