An Observational Study of Molecular profIling of Advanced and aggRessive ENdometrial Cancer and 1-st Line Treatment Approaches in Russian Federation

Recruiting now

Conditions studied: Endometrial Cancer

In brief

Multicenter, observational, prospective study of molecular profiling in advanced and aggressive endometrial cancer patients and 1-st line treatment approaches in Russian Federation

Key facts

Study ID

NCT07041606

Run by

AstraZeneca

People needed

500

Starts

2025-06-24

Expected to finish

2027-06-30

Last updated by the study team

2026-08-10

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female patients aged ≥ 18 years old;
• Signed ICF, including consent for archival FFPE tumor tissue block testing;
• Newly diagnosed, histologically confirmed, advanced (III-IV stage) EC, with the date of diagnosis of histologically confirmed disease within 4 months before inclusion;
• Endometrioid type G3 or any non-endometrioid histological type of EC (such as serous carcinoma, clear cell carcinoma, mixed carcinoma, undifferentiated and dedifferentiated carcinoma, carcinosarcoma, others);
• The presence of biopsy or postoperative archival FFPE tumor sample (block);
• Availability of source medical documentation.

You may not qualify if…

• Patients participating in clinical (interventional) studies since the diagnosis of histologically confirmed, advanced EC.

Where it is running

• Research Site — Arkhangelsk, Russia (enrolling)
• Research Site — Barnaul, Russia (enrolling)
• Research Site — Chelyabinsk, Russia (enrolling)
• Research Site — Irkutsk, Russia (enrolling)
• Research Site — Izhevsk, Russia (enrolling)
• Research Site — Krasnodar, Russia (enrolling)
• Research Site — Krasnoyarsk, Russia (enrolling)
• Research Site — Moscow, Russia (enrolling)
• Research Site — Murmansk, Russia (enrolling)
• Research Site — Ufa, Russia (enrolling)
• Research Site — Yaroslavl, Russia (enrolling)
• Research Site — Yekaterinburg, Russia (enrolling)
• Research Site — Saint Petersburg, Russia (enrolling)
• Research Site — Sochi, Russia (enrolling)
• Research Site — Tomsk, Russia (enrolling)
• Research Site — Tver', Russia (enrolling)
• Research Site — Obninsk, Russia
• Research Site — Vladivostok, Russia
• Research Site — Severodvinsk, Russia

Full record on ClinicalTrials.gov

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