A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Inpatient Adults With Schizophrenia

Completed · Phase 2 · Has a placebo group

Conditions studied: Schizophrenia

In brief

ML-007C-MA-211 is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of orally administered ML-007C-MA in inpatient adult participants aged 18 to 64 years with schizophrenia experiencing an acute exacerbation of psychosis. The primary objective is to evaluate the efficacy of ML-007C-MA compared with placebo in the treatment of subjects with inadequately controlled symptoms of schizophrenia as measured by the Positive and Negative Syndrome Scale (PANSS) Total Score.

Key facts

Study ID

NCT07038876

Run by

MapLight Therapeutics

People needed

307

Starts

2025-06-27

Expected to finish

2026-06-11

Last updated by the study team

2026-07-09

Who can join

Age: 18 and older, up to 64. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Clinical Site — Little Rock, Arkansas, United States
• Clinical Site — Bellflower, California, United States
• Clinical Site — Culver City, California, United States
• Clinical Site — Garden Grove, California, United States
• Clinical Site — Lemon Grove, California, United States
• Clinical Site — Los Angeles, California, United States
• Clinical Site — Montclair, California, United States
• Clinical Site — Orange, California, United States
• Clinical Site — Riverside, California, United States
• Clinical Site — San Diego, California, United States
• Clinical Site — Sherman Oaks, California, United States
• Clinical Site — Torrance, California, United States
• Clinical Site — Hollywood, Florida, United States
• Clinical Site — Miami Lakes, Florida, United States
• Clinical Site — West Palm Beach, Florida, United States
• Clinical Site — Atlanta, Georgia, United States
• Clinical Site — Decatur, Georgia, United States
• Clinical Site — Chicago, Illinois, United States
• Clinical Site — Marlton, New Jersey, United States
• Clinical Site — Staten Island, New York, United States
• Clinical Site — North Canton, Ohio, United States
• Clinical Site — Austin, Texas, United States
• Clinical Site — DeSoto, Texas, United States
• Clinical Site — Richardson, Texas, United States

Full record on ClinicalTrials.gov

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