Investigation of Lymph Node Biology in Kidney Cancer
Recruiting now · Not applicable
Conditions studied: Renal Cell Carcinoma (RCC)
In brief
The purpose of this pilot study is to investigate the phenotype, anti-tumor effector functions, and TCR repertoire of T cells isolated from patient tumor draining lymph nodes (TDLNs) to understand T cell priming and trafficking patterns in Renal Cell Carcinoma (RCC). Data and biospecimen collected will be used for current and future research projects involving the study of kidney cancer biology and related medical conditions. Investigators will use this valuable resource to ask clinically relevant translational questions that pertain to biomarker discovery/validation, identification of novel therapeutic targets, and to better understand the genetic and biological basis of the various kidney cancers.
Key facts
- Study ID
- NCT07038733
- Run by
- Yale University
- People needed
- 33
- Starts
- 2026-01-30
- Expected to finish
- 2030-12-01
- Last updated by the study team
- 2026-06-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Candidates for inclusion include adult patients with either a known or suspected kidney cancer referred to Yale Genitourinary Oncology providers in the Yale Urology, Medical Oncology and Radiation Oncology or Nephrology Departments. These individuals will be receiving clinical evaluation/medical treatment/surgery/procedures at Yale New Haven Hospital or the Smilow Cancer Hospital.
- Participant eligibility will be determined by study investigators and will be offered protocol details. Interested participants will be invited to participate by study investigators. Consent will be obtained by study investigators or other authorized study personnel. Any potential adult participants with known or suspected kidney cancers with a renal mass who are patients of non-study physicians will be invited to participate by study personal only with the approval of their treating physician.
You may not qualify if…
- Participants under the age of 18. Children will not be enrolled on the study.
- Participants known to be pregnant or actively breastfeeding.
- Iodine allergy hypersensitivity.
Where it is running
- Yale University — New Haven, Connecticut, United States (enrolling)
Full record on ClinicalTrials.gov
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