The Use of Sublingual Melatonin Premedication in Geriatric Cataract Surgery

Recruiting now · Phase 4 · Has a placebo group

Conditions studied: Cataract Surgery Anesthesia

In brief

Cataract surgery is routinely performed with anesthesia care, whereas anesthesia care for other elective, low-risk, outpatient procedures is applied more selectively. We hypothesize that sublingual melatonin will provide superior anxiolysis and sedation while maintaining a high safety profile and minimizing hemodynamic disturbances.

Key facts

Study ID

NCT07036367

Run by

Al-Azhar University

People needed

60

Starts

2025-09-01

Expected to finish

2026-06-15

Last updated by the study team

2026-01-07

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• • Age ≥ 60 years
• American Society of Anesthesiologists (ASA) physical status I-III
• Scheduled for unilateral cataract surgery under local anesthesia
• Ability to understand and complete study-related questionnaires

You may not qualify if…

• • Known allergy or hypersensitivity to melatonin
• Chronic use of sedatives, hypnotics, or anxiolytics
• History of sleep disorders or psychiatric illness
• Visual or hearing impairment that would hinder communication
• Emergency surgery or anticipated intraoperative complications

Where it is running

• Al-Azhar University — Baghdad, Baghdad Governorate, Iraq (enrolling)
• Al-Azhar University — Cairo, Egypt, Egypt

Full record on ClinicalTrials.gov

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