CABGpreHAB - a Feasibility Study Protocol
Recruiting now · Not applicable
Conditions studied: Ischaemic Heart Disease, Prehabilitation, Coronary Artery Bypass, Feasibility Studies, Multimodal Intervention, Adult
In brief
Patients with ischemic heart disease (IHD) awaiting coronary artery bypass graft (CABG) surgery often face challenges like advanced age, frailty, comorbidities, and physical inactivity. These factors, combined with the physiological and psychological stress of surgery, can hinder postoperative recovery. Traditionally, strategies to improve surgical outcomes focus on the intra- and postoperative periods. However, the pre-surgery waiting period offers a "window of opportunity" for prehabilitation, which aims to enhance patients' functional capacity through exercise, nutrition, and psychological support. The CABGpreHAB feasibility study evaluates the feasibility of a home-based multimodal prehabilitation intervention for patients awaiting elective CABG surgery. This randomized pilot study compares the intervention plus usual care to usual care alone, assessing feasibility outcomes like recruitment, retention, attrition, fidelity, and adherence. The study aims to optimize a subsequent full-scale randomized controlled trial (RCT) and improve patient outcomes by leveraging the pre-surgery period for prehabilitation.
Key facts
- Study ID
- NCT07035171
- Run by
- Rigshospitalet, Denmark
- People needed
- 50
- Starts
- 2025-06-24
- Expected to finish
- 2026-07-18
- Last updated by the study team
- 2025-06-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Planned to have elective isolated first-time CABG surgery.
- 18 years or older
- Two weeks or more before surgery
- Speaks and understands Danish.
- Gives written informed consent.
You may not qualify if…
- Patient with unstable angina pectoris and/ or MI during the last two weeks.
- Left main stem stenosis >50%
- Left ventricular ejection fraction < 35%
- Significant ventricular arrhythmia
- Orthopedic or neurologic preconditions precluding exercise training.
- Inability to attend the prehabilitation program due to physical limitations.
- Patients who have cognitive deficits that would disqualify prehabilitation.
- Severe heart failure, NYHA Class IV
- Lack of capacity to consent
Where it is running
- The Department of Heart and Lung Surgery, Copenhagen University hospital Rigshospitalet — Copenhagen, Denmark (enrolling)
Full record on ClinicalTrials.gov
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