Pharmacokinetic Study of Topical Phenylephrine

Recruiting now · Early Phase 1

Conditions studied: Chemotherapy Induced Alopecia, Chemotherapy Side Effects

In brief

Pharmacokinetic Study of Topical Phenylephrine

Key facts

Study ID

NCT07033845

Run by

Applied Biology, Inc.

People needed

24

Starts

2025-06-30

Expected to finish

2025-12-28

Last updated by the study team

2025-10-03

Who can join

Age: 18 and older, up to 55. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Healthy females, age 18-55
• BMI: 18-30 kg/m²
• Fitzpatrick Skin Types I-IV (to standardize absorption risk)
• Scalp free from irritation, dermatologic disease, or damage
• Able to refrain from using other topical scalp products

You may not qualify if…

• History of cardiovascular disease, hypertension, or arrhythmia
• Scalp infections, wounds, or significant hair loss
• Recent use of medications that interfere with CYP enzymes or adrenergic systems
• Known sensitivity to phenylephrine or ethanol
• Positive drug screen or abnormal ECG at screening

Where it is running

• University of Rome ("G. Marconi") — Rome, Italy (enrolling)

Full record on ClinicalTrials.gov

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