A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer

Starting soon · Not applicable

Conditions studied: Skin Carcinoma

In brief

This clinical trial studies whether a disposable negative pressure wound therapy (dNPWT) device, SNaP Wound Care System (Ultraportable Mechanically Powered Negative Pressure Wound Therapy) (SNaP), promotes wound healing in the lower limbs in patients that have undergone Mohs micrographic surgery (Mohs surgery) for non-melanoma skin cancer. Mohs surgery is a surgical technique used to treat skin cancer. Individual layers of cancerous tissue are removed and examined under a microscope one at a time until all cancerous tissue has been removed. It is an important part of removing skin cancer, but it often leads to soft-tissue defects and reconstructive challenges, especially in high-tension areas like the lower limbs. Typically, these wounds are managed by leaving them open and allowing them to heal from the base up or are reconstructed by transferring healthy skin from another part of the body. Negative pressure wound therapy (NPWT) is a wound dressing system that continuously or intermittently applies subatmospheric pressure to the surface of a wound to draw out fluid and promote healing. The SNaP device is a dNPWT device for lower leg wound healing designed for increased portability and ease of use outside of a hospital setting. It is a modification of traditional NPWT devices that uses springs to generate pressure, making it lighter and more user-friendly than traditional devices that rely on electrically powered pumps. This may be a more effective way to promote wound healing in the lower limbs following Mohs surgery for non-melanoma skin cancer.

Key facts

Study ID

NCT07032701

Run by

Jonsson Comprehensive Cancer Center

People needed

60

Starts

2026-12-01

Expected to finish

2031-06-01

Last updated by the study team

2026-07-01

Who can join

Age: 19 and older, up to 79. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 19 to 79 years
• Presenting with a lower limb wound following Mohs surgery for non-melanoma skin cancer, designated to heal by secondary intention
• Wound size less than 13 cm x 13 cm
• Patient capable of changing the SNAP-therapy system at home

You may not qualify if…

• History of diabetes mellitus
• History of venous insufficiency
• History peripheral arterial disease
• Chronic steroid use (defined as great than 6 weeks) within the last one year
• History of HIV
• History of chemotherapy use within the last one year
• History of smoking exceeding 10 pack-years or current smoker
• History of stroke
• History of deep venous thrombosis
• Active infection
• Allergy to adhesives
• Wounds with visible bone, tendon, ligament, nerve

Where it is running

• UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.