Association of Genetic Variants With Myopia

Recruiting now

Conditions studied: Myopia

In brief

This study aims to identify genetic factors linked to myopia, including those that influence a person's risk of developing it and how quickly it progresses (like changes in eye length). It will also examine how different treatments-such as low-dose atropine drops, orthokeratology lenses, specialized glasses, and increased outdoor time-interact with these genes. Finally, the research will develop a genetic risk score to help tailor personalized myopia prevention and treatment plans.

Key facts

Study ID

NCT07030153

Run by

Beijing Visionly Plus Eye Hospital

People needed

1000

Starts

2025-07-01

Expected to finish

2028-12-31

Last updated by the study team

2025-06-22

Who can join

Age: 6 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 6-18 years.
• Any Spherical equivalent refraction (SER)
• Parental consent for genetic testing.

You may not qualify if…

• Suspected genetic syndromes (e.g., Stickler, Marfan).
• Other eye diseases (e.g., glaucoma, cataracts, retinal abnormalities, strabismus).
• Prior refractive surgery

Where it is running

• Beijing New Vision Eye Hospital — Beijing, China (enrolling)
• Beijing Visionly Plus Eye Hospital — Beijing, China (enrolling)

Full record on ClinicalTrials.gov

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