Echocardiography Guided TAVR (Echo TAVR)

Recruiting now

Conditions studied: Transcatheter Aortic Valve Replacemen, Echocardiography

In brief

Conventional transcatheter aortic valve replacement (TAVR) relies on fluoroscopic and contrast agents. However, in high-risk patients, exposure to ionizing radiation and contrast agents is contraindicated and undesirable. Echocardiography guidance TAVR can offer a feasible and safer strategy for TAVR.

Key facts

Study ID

NCT07030062

Run by

Pan Xiangbin

People needed

20

Starts

2025-02-18

Expected to finish

2025-12-31

Last updated by the study team

2025-06-19

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• symptomatic severe AS determined by echocardiography and Doppler that requiring aortic valve replacement, which is defined as: mean gradient ≥40 mmHg, peak aortic velocity ≥4 m/s, and aortic valve area (AVA) ≤1 cm2 (or an indexed AVA ≤0.6 cm2/m2);
• a history of malignancy or a high familial risk of cancer, with refusal to undergo contrast- or radiation-guided procedures;
• chronic kidney disease and refuse to receive contrast agents or radiation exposure.

You may not qualify if…

• Required hybrid procedures or concomitant interventions on other cardiac malformations; Deemed inoperable due to extremely high surgical risk or severe comorbidities; Had untreated clinically significant coronary vascular disease amenable to revascularization; Previously undergone aortic valve replacement.

Where it is running

• Fuwai Hospital — Beijing, China (enrolling)

Full record on ClinicalTrials.gov

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