A Randomized Double Blind, Placebo Controlled Clinical Study Evaluating the Efficacy and Safety of Magnesium Supplementation on Relaxation in Adults

Starting soon · Not applicable · Has a placebo group

Conditions studied: Healthy

In brief

The study will assess the efficacy of magnesium supplementation for improvement of body and mind relaxation (through stress levels), and sleep score compared to placebo, assessed by validated questionnaires. Participants will be asked to take the supplement every day for 12 weeks and will complete monthly check-ins and questionnaires. Participants will monitor adverse events in a journal.

Key facts

Study ID

NCT07029607

Run by

Olly, PBC

People needed

100

Starts

2025-07-14

Expected to finish

2025-10-24

Last updated by the study team

2025-06-19

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy participants (women + men)
• Will maintain regular diet and exercise habits
• Agreement to adhere to the procedures and requirements of the study and to report to the institute on the day(s) and at the time(s) scheduled for the assessments.

You may not qualify if…

• Neurological or psychiatric disorders
• Pregnant or breastfeeding
• Known allergies to magnesium-containing products
• Taking a medication known to interact with magnesium, or taking loop diuretics, cyclosporine, digoxin, amphotericin.
• No concurrent magnesium supplementation
• Substance or alcohol abuse
• Currently use, or have used within appropriate washout period, any prescription, over the counter medication, or supplements with primary CNS activity such as Antidepressants,mood stabilizer and anxiolytics, Sedatives and Stimulants
• Anticholinergic or cholinergic medications
• Anti-inflammatory and analgesic medication (except for PRN use)
• Anti-allergy medication (except for non-sedating antihistamines)
• Blood thinners
• Other prescribed medications that may affect cognition, stress, or mood
• Body mass index (BMI) greater than 40 kg/m2 ,
• Individuals on angiotensin converting enzyme inhibitors for blood pressure control, other magnesium-retaining drugs, or potassium-sparing drugs
• History of reaction to the category of product tested
• Other diseases or medications that might directly interfere in the study or put the subject's health under risk.
• Subjects with any invasive medical procedures during the study.
• Participants who are unreliable or unlikely to be available for the duration of the study.
• No employees of PCR or the sponsor (e.g OLLY PBC, Unilever, or the H\&W Collective)

Where it is running

• Princeton Consumer Research — St. Petersburg, Florida, United States

Full record on ClinicalTrials.gov

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