Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Cirrhosis, Frailty, Sarcopenia

In brief

Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipate that this combination of supplementation and nutrition/exercise prehabilitation app will maintain muscle health in patients with liver disease.

Key facts

Study ID

NCT07029243

Run by

University of California, San Francisco

People needed

100

Starts

2026-04-15

Expected to finish

2026-12-01

Last updated by the study team

2026-07-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed diagnosis of cirrhosis by ICD-10 code, liver biopsy, abdominal imaging, or transient elastography
• Access to digital device and internet at home
• Ability to provide written informed consent before any study-related activities
• Ability to remain in study for at least 3 months

You may not qualify if…

• Allergy to milk protein
• On hemodialysis
• No English language proficiency
• Presence of condition or abnormality that in opinion of the Investigator will compromise safety of the patient or quality of the data
• Concomitant severe underlying systemic illness that in the opinion of the Investigator would interfere with completion of study
• Pregnant, breastfeeding, or intention of becoming pregnant during study time frame

Where it is running

• University of California San Francisco — San Francisco, California, United States (enrolling)

Full record on ClinicalTrials.gov

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