Noninvasive Intratumor Heterogeneity Evaluation in HNSCC
Recruiting now
Conditions studied: Head and Neck Cancer
In brief
This study focuses on tumor heterogeneity, a core challenge in the field of oncology, and innovatively utilizes patient imaging data to deeply mine and analyze intratumoral heterogeneity. By constructing an imaging analysis model for tumor heterogeneity and associating this model with clinical, pathological, transcriptomic, and metabolomic data of patients, a multi-omics decoding of tumor heterogeneity is achieved. The main questions it aims to address are: Can the ITH model stratify patients' treatment efficacy and prognosis assessment? Can pathological and multi-omics sequencing map the mechanisms behind the ITH model?
Key facts
- Study ID
- NCT07027280
- Run by
- First Affiliated Hospital of Chongqing Medical University
- People needed
- 700
- Starts
- 2025-02-27
- Expected to finish
- 2025-08-15
- Last updated by the study team
- 2025-06-18
Who can join
Age: 15 and older, up to 89. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Pathologically confirmed head and neck squamous cell carcinoma (HNSCC). Complete clinical, imaging, and pathological data. Available complete follow-up information.
You may not qualify if…
- Patients who received chemotherapy or radiotherapy before surgery. Poor image quality. Tumors too small to be easily identified. History of other concurrent malignant tumors.
Where it is running
- The First Affiliated Hospital of Chongqing Medical University — Chongqing, China (enrolling)
Full record on ClinicalTrials.gov
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