Enhancing Smoking Cessation for African American People Everywhere

Recruiting now · Phase 2

Conditions studied: ESCAPE Intervention+NRT, quitSTART Intervention+NRT, CTRL+NRT

In brief

The present study aims to investigate the efficacy of an mHealth smoking cessation and HIV disease management intervention among a nationally representative sample of African America/Black (hereafter refer to as Black) persons with HIV/AIDS (PWH) who smoke cigarettes. Participants will be randomized into one of three conditions: (1) the intervention, ESCAPE (Enhancing Smoking Cessation for African American People Everywhere) + Nicotine Replacement Medications (NRT), (2) the National Cancer Institute's (NCI) quitSTART app, the standard mobile smoking cessation treatment + NRT, and (3) an assessment-only control group + NRT.

Key facts

Study ID

NCT07024992

Run by

University of Houston

People needed

300

Starts

2026-06-30

Expected to finish

2029-06-30

Last updated by the study team

2026-07-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• At least 18 years of age
• Identify as Black/African American
• Living with HIV
• Biochemical verification of self-reported smoking status following minimum study specified smoking rate endorsement
• Motivated to quit smoking
• Must be ready to quit cigarettes within 14 days of full enrollment
• Moderate or higher anxiety sensitivity OR elevated anxiety OR depression
• Must be willing to download a mobile app onto their personal phone
• Must be willing to use NRT
• Possess an Android/Apple smartphone that is compatible with the mobile app
• Demonstrate 7th grade level proficiency in English (≥4 on the Rapid Estimate of Adult Literacy in Medicine-Short Form [REALM-SF])
• Valid proof of identification (photo of valid US ID)

You may not qualify if…

• Legal situations which may interfere with study participation
• Not being fluent in English
• High blood pressure that is not under control
• Having experienced a heart attack within the past 2 weeks
• Pregnant of planning to become pregnant within the next six months

Where it is running

• University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States (enrolling)

Full record on ClinicalTrials.gov

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