PRecision biomArker-Guided MAnagement of TuberculosIs Contacts: a Discrete Choice Experiment

Recruiting now

Conditions studied: Tuberculosis (TB)

In brief

This study is part of a broader programme of work to develop and pilot a randomised-controlled trial of new tests to identify people who will benefit most from preventive treatment for tuberculosis (TB). The aim of the current study is to explore factors affecting patient decisions to start preventive treatment. The specific objectives are to understand how patients make decisions about preventive treatment initiation for TB (stage 1); and to design and conduct a "discrete choice experiment" survey to further evaluate preferences (stage 2).

Key facts

Study ID

NCT07024836

Run by

University College, London

People needed

430

Starts

2025-05-22

Expected to finish

2026-12-01

Last updated by the study team

2025-06-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (aged ≥18 years) who have been tested for latent TB infection in routine clinical services, or are eligible for testing. Eligible people for testing include migrants from countries with high TB incidence (entered UK within 5 years), people with recent contact with a person with TB disease, and people eligible for LTBI screening prior to starting immunosuppression or through occupational health testing.

You may not qualify if…

• Unable to provide informed consent.

Where it is running

• Whittington Hospital — London, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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