Predicting and Monitoring Spontaneous Bacterial Peritonitis in Cirrhotic Patients Using the Mansoura Scoring System

Starting soon

Conditions studied: Spontaneous Bacterial Peritonitis

In brief

The aim of this prospective study was to examine predictors of SBP in order to develop a noninvasive method to identify or exclude an episode of SBP, for starting early treatment with antibiotics, so decrease morbidity and mortality in these patients.

Key facts

Study ID

NCT07024355

Run by

Assiut University

People needed

250

Starts

2026-04-01

Expected to finish

2027-04-01

Last updated by the study team

2026-01-22

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients aged >18 years
• Diagnosed liver cirrhosis
• Presence of ascites
• Provided written informed consent

You may not qualify if…

• Use of antibiotics within the previous two weeks
• Prophylactic treatment for spontaneous bacterial peritonitis (SBP) prior to admission
• Ascites not related to portal hypertension, including:
• Peritoneal tuberculosis
• Peritoneal carcinomatosis
• Congestive heart failure
• Renal disease
• Pancreatitis
• Hemorrhagic ascites
• Secondary peritonitis
• Presence of infections other than SBP, including:
• Pneumonia
• Urinary tract infection
• Skin and soft tissue infection
• Presence of malignancy Hematologic diseases
• Use of antiplatelet drugs or non-steroidal anti-inflammatory drugs (NSAIDs)
• Receipt of platelet or blood transfusion prior to admission
• Diseases associated with elevated mean platelet volume (MPV), including:
• Diabetes mellitus
• Cardiovascular disease
• Hyperthyroidism
• Immune thrombocytopenia
• Myeloproliferative disorders

Full record on ClinicalTrials.gov

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