Sepsis and Hospital Mortality
Recruiting now
Conditions studied: Sepsis
In brief
Sepsis is one of the leading causes of hospital mortality, with a rate of approximately 20% (World Health Organization) among vulnerable patients admitted to high-intensity care units such as CCUs and inpatient wards. Currently, diagnostic criteria such as the Systemic Inflammatory Response Syndrome (SIRS) and the Sequential Organ Failure Assessment (SOFA) score, although widely used, lack sufficient specificity and accuracy. No established parameters are available for early and timely diagnosis. This study aims to address this gap by investigating the variability of blood plasma conductivity and dielectric constant using microwave probes previously validated for non-invasive glucose monitoring. The acquired data will be analyzed using the Anritsu VectorStar VNA to identify innovative and reliable parameters associated with the presence of severe infections.
Key facts
- Study ID
- NCT07022041
- Run by
- University of Calabria
- People needed
- 100
- Starts
- 2025-07-15
- Expected to finish
- 2026-12-15
- Last updated by the study team
- 2025-08-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 18 years
- Cardiology patients without documented infection (Control Group)
- Patients with sepsis
- Patients with nosocomial infection
- Patients with myocarditis, endocarditis, or pericarditis
- Ability to provide written informed consent
You may not qualify if…
- Patients with severe or chronic medical conditions that may interfere with study results, such as autoimmune diseases, renal or hepatic failure
- Patients taking medications that could affect the measured biophysical parameters, such as corticosteroids or immunosuppressants
- Patients with cancer
- Patients with diseases involving the immune system (e.g., lymphomas, leukemias)
- Patients with congenital or acquired immunodeficiencies (e.g., HIV)
- Patients who are unable to read and sign the informed consent form
Where it is running
- ''Annunziata'' Hospital — Cosenza, Italy (enrolling)
Full record on ClinicalTrials.gov
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