Short-term and Intermediate-term Effects of Self-applied Joint Mobilization Versus Clinician-applied Joint Mobilization in Addition to Exercise in Patients With Knee Osteoarthritis: A Randomized Clinical Trial

Starting soon · Not applicable

Conditions studied: Knee Osteoarthritis

In brief

The goal of this clinical trial is to learn if a combination of patient self-administered joint mobilization and exercise works to treat knee osteoarthritis in adults. The main questions it aims to answer are: * Does self-administered joint mobilization improve the ability to perform regular daily activities? * Does self-administered joint mobilization improve knee motion? * Does self-administered joint mobilization improve hip strength? Researchers will compare the program of self-administered joint mobilization to a joint mobilization administered by a physical therapist. Participants will: * Attend 8-12 physical therapy clinic visits over 6 - 8 weeks * Perform home exercises * Visit the clinic 6 months later for a brief check-up

Key facts

Study ID

NCT07020897

Run by

Texas Woman's University

People needed

24

Starts

2025-07-15

Expected to finish

2026-11-30

Last updated by the study team

2025-06-13

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meets National Institute for Health and care Excellence (NICE) criteria for knee osteoarthritis:
• Age 45 years or older
• Movement-related knee pain
• No morning stiffness or morning stiffness < 30 minutes
• Knee flexion contracture (kFC) at least 1cm, measured by heel-height
• Fluency in verbal and written English for completion of outcome measure and screening, and to take directions.
• Able to attend all study-related appointments

You may not qualify if…

• Assistive device required for ambulation
• Systemic disease affecting joint function (diabetes, rheumatological disorders, etc)
• Previous lower extremity joint replacement
• Lower quarter surgery, injection, or therapy in the past year
• Other functionally-limiting physical impairment of the lower quarter
• Spine or lower extremity compensation claim (work, accident, etc)

Where it is running

• Texas Health Resources Sports Medicine Allen — Allen, Texas, United States
• Texas Health Resources Plano Presbyterian Outpatient Rehabilitation — Plano, Texas, United States

Full record on ClinicalTrials.gov

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