Using 3D Kidney Model Based on Artificial Intelligence to Assist Partial Nephrectomy: A Prospective Validation Study

Recruiting now · Not applicable

Conditions studied: Renal Cell Cancer

In brief

The goal of this study is to develop a real-time artificial intelligence-driven 3D kidney model to assist robotic or laparoscopic partial nephrectomy: • Can this AI-powered model optimize the workflow of partial nephrectomy and enhance surgical benefits?

Key facts

Study ID

NCT07020169

Run by

Shao Pengfei

People needed

232

Starts

2025-05-01

Expected to finish

2027-03-01

Last updated by the study team

2025-06-13

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 18-80 years, regardless of gender
• Written informed consent obtained from the patient or legally authorized representative after full protocol disclosure
• Preoperative imaging (CT/MRI) confirming clinical stage T1a or select T1b renal tumors suitable for partial nephrectomy (R.E.N.A.L. nephrometry score ≤10)
• Localized renal tumors without lymph node/distant metastasis per NCCN Guidelines® (v2023)
• Elective minimally invasive partial nephrectomy (laparoscopic/robotic) after comprehensive surgical counseling

You may not qualify if…

• Multifocal renal tumors (bilateral or unilateral)
• Prior systemic anticancer therapy (targeted agents/immunotherapy/chemotherapy) within 6 months
• Absolute surgical contraindications (e.g., ASA class ≥IV, uncontrolled coagulopathy)
• Intraoperative conversion to radical nephrectomy or open approach
• Postoperative adjuvant therapy during protocol-defined follow-up (12 months)
• Major comorbidities (e.g., NYHA class III/IV heart failure, eGFR <30 mL/min/1.73m²) affecting outcome assessment
• Concurrent enrollment in interventional clinical trials
• Investigator-determined ineligibility based on risk-benefit analysis

Where it is running

• The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital) — Nanjing, Jiangsu, China (enrolling)
• The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital) — Nanjing, Jiangsu, China

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.