Burning Mouth Syndrome: Symptoms and Management

Recruiting now · Early Phase 1

Conditions studied: Burning Mouth Syndrome

In brief

This research study aims to evaluate how an oral cooling spray, currently a commercial dietary supplement, impacts symptoms associated with burning mouth syndrome (BMS). This study will examine symptoms, frequency, and severity, along with other related side effects of BMS on food intake, enjoyment, and quality of life.

Key facts

Study ID

NCT07016555

Run by

University of Massachusetts, Amherst

People needed

50

Starts

2025-06-11

Expected to finish

2025-12-15

Last updated by the study team

2025-06-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have buring mouth syndrome or experience oral burn
• Live in the United States
• At least 18 years old
• Having been diagnosed or suspected diagnosis of burning mouth syndrome or suffer from chronic oral burn without any identifiable causative lesion
• No tongue or cheek piercings
• No history of cancer
• No recent or scheduled dental treatment
• No history of gum disease
• No aversions to mint or hop extracts

You may not qualify if…

• Have recently undergone dental treatment in the last three months or have plans to undergo dental treatment (e.g., fillings, crowns, root canals, extractions, or other dental procedures) in the coming month.
• Have started any new treatments for BMS in the last 3 months or have plans to start new treatments in the coming month.

Where it is running

• UMass Amherst — Amherst, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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