Characterising the Neuromuscular Function of Post Stroke Patients
Recruiting now
Conditions studied: Stroke (CVA) or TIA
In brief
Strokes are a leading cause of death and disability in developed countries, with significant economic and social impacts. Defined by the WHO, strokes cause rapid and lasting disturbances in cerebral function. In the UK, strokes occur every five minutes, affecting 100,000 people annually and resulting in substantial physical impairments and financial costs. Although stroke-related deaths have decreased due to improved treatments and awareness, strokes remain a major cause of death and disability worldwide, especially in lower-income countries. Strokes typically cause unilateral deficits, leading to significant daily challenges and necessitating tailored rehabilitation strategies such as CIMT, FES, and VR Rehab. As the population ages, innovative neurorehabilitation approaches are essential to enhance functional recovery post-stroke. This pilot study aims to better understand the neuromuscular deficits caused by stroke to inform and improve future rehabilitation interventions, including the potential use of force accuracy training (FAT)
Key facts
- Study ID
- NCT07013188
- Run by
- University of Nottingham
- People needed
- 16
- Starts
- 2024-06-01
- Expected to finish
- 2026-05-01
- Last updated by the study team
- 2025-06-10
Who can join
Age: 40 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- • Aged between 40-85 years
- Willing and able to give informed consent for participation in the study
- Had a confirmed stroke within the last 5 years
- Self-reports persisting post-stroke loss of unilateral limb function
You may not qualify if…
- • Diagnosis of cognitive impairment/dementia
- Current or recent (<2y) malignancy
- Severe respiratory disease (e.g., uncontrolled asthma, COPD, pulmonary hypertension)
- Active cardiovascular disease: Uncontrolled hypertension (BP>160/100mmHg); Recent (<12mo) cardiac event; Heart failure (Class III/IV); Significant arrhythmia; Unstable angina
- Metabolic disease: Untreated hyper/hypoparathyroidism; Cushing's disease
- Significant musculoskeletal disorders (based on clinical opinion)
- Dialysis patients
- Recent steroid treatment within 6 months or hormone replacement therapy
- Mobility dependant (wheelchair dependency)
Where it is running
- Royal Derby Hospital branch, School of Medicine, University of Nottingham — Derby, Derbyshire, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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