Care in Multiple Sclerosis (MS)

Recruiting now

Conditions studied: Multiple Sclerosis

In brief

This study is structured around three main aims. In Aim 1, investigators will conduct community-based participatory research (CBPR) to develop culturally tailored methods to assess childhood adversity in multiple sclerosis (MS). Aim 2 will investigate the impact of childhood adversity on MS outcomes among individuals with relapsing-remitting MS (RRMS), among whom 70% belong to a group historically under-represented in MS research: Black, Hispanic, or poverty-impacted. Aim 2 procedures involve two visits that include a research blood draw and an MRI scan. In Aim 3, investigators will conduct interviews and surveys to explore environmental and social factors affecting quality of life for minority MS patients.

Key facts

Study ID

NCT07011914

Run by

NYU Langone Health

People needed

300

Starts

2025-10-23

Expected to finish

2029-06-30

Last updated by the study team

2026-05-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aim 1 -
• aged ≥18-29 years
• diagnosis of RRMS (Fulfill international criteria for relapsing remitting (RRMS))
• 70% self-identifying as a Black, Hispanic, or poverty-impacted (up to 138% of the federal poverty level) individual,and
• fluent in English or Spanish.
• Aim 2 -
• aged ≥18-29 years
• diagnosis of RRMS (Fulfill international criteria for relapsing remitting (RRMS))
• 70% self-identifying as a Black, Hispanic, or poverty impacted, and
• fluent reading in English or Spanish
• Pediatric onset MS (MS onset before age 18 and age at time of enrollment is 18-25) OR adult-onset MS (MS onset at age 18 or older and age at time of enrollment is 19-29)
• Disease duration below 8 years
• Aim 3 -
• Aim 3 will enroll the first 20 participants from Aim 2 who meet the following criteria:
• completed at least 80% of study data in the cross-sectional study/Aim 2.
• a total of 70% must self-identify as Black, Hispanic, or meet criteria for poverty impacted.
• interviews will be evenly split between participants with high (top quartile) and low (bottom quartile) of PROMIS-10 scores.

You may not qualify if…

• Primary or Secondary Progressive MS
• Inability to consent.
• MS relapse within 30 days prior to study entry
• Other major neurologic or psychiatric illness

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States (enrolling)
• University of California, San Francisco — San Francisco, California, United States (enrolling)
• University of Colorado Denver — Aurora, Colorado, United States (enrolling)
• Massachusetts General Hospital — Boston, Massachusetts, United States (enrolling)
• Cleveland Clinic — Cleveland, Ohio, United States (enrolling)
• Baylor College of Medicine — Houston, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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