Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct Stones
Recruiting now · Not applicable
Conditions studied: Gall Stone, Common Bile Duct Calculi, Cholecystitis, Chronic, Choledocholithiasis, Periampullary Diverticula
In brief
Chronic calculous cholecystitis in pediatric patients leads to choledocholithiasis in about 12% of cases. These patients require removal of stones from the common bile duct. The most common method of cleaning the common bile duct is endoscopic retrograde cholangiopancreatography, and the standard technique for removing the gallbladder is laparoscopic cholecystectomy. There are different approaches to the treatment of this category of patients: laparoscopic common bile duct exploration (LCBDE), laparoendoscopic rendezvous method (LERV) and one-stage LC( laparoscopic cholecystectomy) after ERCP( endoscopic retrograde cholangiopancreatography). The aim of this prospective study is to evaluate the efficacy and safety Laparoendoscopic rendezvous for difficult cholecystocholedocholithiasis.
Key facts
- Study ID
- NCT07008170
- Run by
- Minia University
- People needed
- 80
- Starts
- 2025-06-15
- Expected to finish
- 2026-07-15
- Last updated by the study team
- 2025-06-19
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients having stone(s) in the gallbladder and concurrent common bile duct , as determined by MRCP(magnetic resonance cholangiopancreatography) or US.
- Patients with acute cholecystitis, acute cholangitis, obstructive jaundice, and those with highly suspicious criteria for common bile duct stones, such as dilated CBD( common bile duct ) on US examination > 7 mm in diameter without obvious common bile duct stones, high serum bilirubin level, and/or high serum alkaline phosphatase level, were also included in this study. (high risk for cholecystocholedocholithiasis)
- Previous failed ERCP attempt
- Patients fit for general anesthesia and tolerant of pneumoperitoneum and endoscopic procedures.
You may not qualify if…
- History of hepatobiliary surgery as choledochoduodenal anastomosis
- A Previous upper abdominal surgery as total or partial gastric resection.
- Morbid obesity.
- Uncorrectable coagulopathy.
- Patients who refused to give consent.
- Pregnancy.
- Suspected malignant biliary stricture or cholangiocarcinoma
- Severe acute cholangitis with hemodynamic instability or septic shock requiring immediate biliary drainage (may necessitate emergent ERCP or percutaneous drainage first)
- Impacted CBD stones or stones deemed too large for endoscopic extraction (e.g., > 1.5 cm)
- Severe cardiopulmonary disease significantly increasing operative risk.
- Intrahepatic bile duct stones with indications for surgery.
- Patients with choledocholithiasis >2 cm or a large number of stones were difficult to remove.
Where it is running
- Liver and GIT hospital , Minia University — Minya, Egypt (enrolling)
Full record on ClinicalTrials.gov
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