Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation

Recruiting now · Phase 4

Conditions studied: Patella Fracture

In brief

The objective of this study is to demonstrate the safety and efficacy of an intra-articular analgesics cocktail injection for post-operative patella fracture fixation patients, by comparing post-operative pain relief and functional recovery among study subjects who received the injection and those who did not receive the injection. Secondary objective is to demonstrate the health economic effects of intra-articular analgesics cocktail injection by reducing length of hospital stay and reducing bed-stay related complications.

Key facts

Study ID

NCT07006168

Run by

The University of Hong Kong

People needed

56

Starts

2024-11-01

Expected to finish

2027-07-31

Last updated by the study team

2025-06-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• acute patella fracture requiring open reduction and internal fixation;
• able to consent to surgery;
• pre-morbid able to ambulate

You may not qualify if…

• open fracture;
• polytrauma;
• previous knee arthroplasty;
• history of chronic pain,
• insulin-dependent diabetes mellitus, or peptic ulcer disease;
• chronic users of glucocorticoids, immunosuppressants, or immune-modulating agents, or of strong opioids (e.g.: morphine, fentanyl, hydromorphone, methadone, oxycodone, or meperidine);
• hepatitis B or C carrier;
• renal impairment (creatinine [Cr], >200 mmol/L)

Where it is running

• Queen Mary Hospital, The University of Hong Kong — Hong Kong, Hong Kong, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

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