Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）

Recruiting now · Not applicable

Conditions studied: Esophageal Cancer, Drainage/Methods, Postoperative Pain

In brief

This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.

Key facts

Study ID

NCT07004634

Run by

Ruijin Hospital

People needed

75

Starts

2025-04-30

Expected to finish

2026-08-01

Last updated by the study team

2025-06-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years
• Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions)
• ASA physical status class I-III

You may not qualify if…

• History of chronic pain or long-term use of analgesics prior to surgery
• Severe cardiopulmonary dysfunction (e.g., FEV1 <50%)
• Coagulation disorders or patients undergoing reoperation
• Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion

Where it is running

• Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine — Shanghai, Shanghai Municipality, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.