Proving Utility of a New Field-cycling MRI Prototype in Acute Stroke Patients

Recruiting now

Conditions studied: Stroke Acute

In brief

The goal of this study is to test if a new type of MRI scanner, called Field-Cycling Imaging (FCI), can show changes in the brain within the first day of a stroke due to a blocked blood vessel or bleeding in the brain. The main question it aims to answer is: • Can FCI identify brain tissue that might recover within the first few hours after a stroke begins? Participants will undergo a standard MRI scan and an FCI scan, as soon as possible after hospital admission. Participants who have had a blocked blood vessel will also provide a blood sample and will have a follow up visit at 30 days for repeat of both scans and providing another blood sample.

Key facts

Study ID

NCT07004140

Run by

University of Aberdeen

People needed

40

Starts

2025-09-16

Expected to finish

2026-05-01

Last updated by the study team

2026-01-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Acute stroke (<24 hours from symptom onset).
• NIHSS ≥4 and <25 with cortical involvement and/or large vessel occlusion on baseline imaging.
• Able to undergo 3T and FCI MRI <24h of onset.
• With or without thrombolysis.

You may not qualify if…

• Contraindications to MRI.
• Medically unstable.
• Unable to comprehend or comply with instructions regarding scanning
• Prior mRS of >3.
• Identified for thrombectomy.
• Non-stroke pathology or previous cortical infarct on CT scan > 1/3 of middle cerebral artery territory.

Where it is running

• University of Aberdeen — Aberdeen, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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