Neural Control and Mechanosensation in Spine Muscle
Enrolling by invitation · Not applicable
Conditions studied: Low Back Pain and Core Muscle, Disc Herniation
In brief
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization. Lumbar spine muscle is compromised in LBP, and do, and do not, respond to exercise based physical therapy program depending on measurements representing activation capacity of lumbar muscle. Here, we will characterize the neurological and muscle specific features that may contribute to limited activation in an attempt to identify sources of resistance to recovery in patients with chronic disc injury and identify precision rehabilitation approaches for this complex population of individuals.
Key facts
- Study ID
- NCT07003802
- Run by
- University of California, San Diego
- People needed
- 152
- Starts
- 2025-07-01
- Expected to finish
- 2030-05-01
- Last updated by the study team
- 2026-05-01
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Surgical group:
- Individuals diagnosed with chronic disc injury (symptoms > 3 months),
- Individuals planning to undergo a spinal surgery to address the diagnosis of chronic disc injury
- Physical Therapy Group-
- Individuals diagnosed with chronic disc injury (symptoms >3 months),
- Individuals initiating an exercise-based physical therapy program to address the diagnosis of chronic disc injury
- Healthy Control group -
- Individuals with no history of chronic back pain (interfering pain lasting >3 months) within the past 3 years,
- no significant spinal pathology beyond normal age-related degenerative changes
You may not qualify if…
- Surgery/Physical therapy groups-History of lumbar spine surgery
- Diabetes
- Neuromuscular diseases
- Epilepsy or other seizure disorder -Healthy control group -
- History of lumbar spine surgery
- History of interfering pain lasting >3 months
- Diabetes
- Neuromuscular diseases
- Epilepsy or other seizure disorder
Where it is running
- UC San Diego — La Jolla, California, United States
Full record on ClinicalTrials.gov
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