Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support
Recruiting now · Not applicable
Conditions studied: Prescribing Patterns, Physician, Physician's Practice Patterns, Drug Utilization Review
In brief
The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescribed, and the study team has identified that the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority. This evaluation of PPI order panel variations is embedded within UCLA's existing EHR system, ensuring that changes are tested pragmatically within routine workflows. The study aims to determine whether small adjustments to the order panel can better align prescribing patterns with clinical best practices while maintaining physician autonomy.
Key facts
- Study ID
- NCT06998966
- Run by
- University of California, Los Angeles
- People needed
- 372
- Starts
- 2026-06-01
- Expected to finish
- 2027-06-01
- Last updated by the study team
- 2026-04-29
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- UCLA Health primary care physicians who have a clinical full-time equivalency of at least 25%.
You may not qualify if…
- Physicians with a clinical full-time equivalency of less than 25%
Where it is running
- UCLA Health System — Los Angeles, California, United States (enrolling)
Full record on ClinicalTrials.gov
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