Trial of Pistachio Consumption in Older Adults
Running, not enrolling · Not applicable
Conditions studied: Cognition, Cardiometabolic Risk Factors, Life Satisfaction
In brief
The goal of this study is to evaluate whether a pistachio-enriched diet leads to changes in cognitive function, cardiometabolic risk factors, and life satisfaction in older adults over a 6-month period.
Key facts
- Study ID
- NCT06992544
- Run by
- Brigham and Women's Hospital
- People needed
- 97
- Starts
- 2025-05-28
- Expected to finish
- 2026-07-01
- Last updated by the study team
- 2026-06-03
Who can join
Age: 65 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Active participant in COSMOS
- Current age 65 to 80 years
- Does not reside in the states of Arizona, Hawaii, or Wyoming (since Quest Diagnostics does not have locations in these states)
You may not qualify if…
- Tree nut allergy
- Current intake of pistachios, peanuts, walnuts, or other nuts >1 serving/week
- Diagnosis of Alzheimer's disease or any other type of dementia
- Diagnosis of cancer or CVD (MI, stroke, CABG, PTCA, or stent) within last 12 months
- Changes in the dose or number of anti-hypertensive, lipid-lowering, or diabetic medications over the past 3 months prior to randomization
- Does not own a smartphone or tablet
- Unable or unwilling to abstain from pistachio intake for 6 months
- Unable or unwilling to limit nut consumption to ≤1 serving/week for 6 months
- Unable or unwilling to complete online questionnaires and cognitive assessments
- Unable or unwilling to travel to a local Quest site for biospecimen collection
- Unable or unwilling to provide consent to participate in the trial
- Failure to complete the baseline Life Satisfaction Questionnaire
- Failure to complete the baseline cognitive assessments
- Failure to complete the baseline biospecimen collection
Where it is running
- Brigham and Women's Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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